It is only possible to stay in the UK under the Start Up category for a maximum period of 2 years. As such, this category does not lead to settlement.
Depending on the route you take at the end of your Start Up visa, you may become eligible for ILR under your new visa.
For example, should you switch from the Start Up visa to the Innovator route – the Innovator visa does lead to settlement where the individual meets the relevant requirements, including 3 continuous years residence in the UK.